Las Vegas Raiders head coach Klint Kubiak is fired up after the Raiders intercept on the New York Jets at Met Life Stadium in East Rutherford NJ on Sun Nov 1, 2026 (AP News photo)

Las Vegas Raiders podcast Rich Perez:

1. Can Kirk Cousins keep the Raiders’ offense rolling against San Francisco? After the Raiders’ 38–33 victory over the New York Jets, can Cousins maintain his momentum against a 49ers defense led by Fred Warner and Nick Bosa?

2. Can Brock Bowers be the difference-maker for Las Vegas? Will the Raiders’ dynamic tight end create matchup problems for San Francisco’s linebackers and secondary, particularly in the red zone?

3. Can Brock Purdy exploit the Raiders’ defensive weaknesses? Will Purdy find success throwing to George Kittle and Brandin Cooks, especially if Las Vegas struggles to pressure him?

4. Which running game will control the tempo? Can Ashton Jeanty establish himself against San Francisco’s defensive front, or will Christian McCaffrey give the 49ers the edge with his rushing and receiving ability?

5. Will Maxx Crosby and the Raiders’ pass rush disrupt San Francisco’s offense? Can Crosby put pressure on Purdy and force turnovers, or will Trent Williams and the 49ers’ offensive line keep the quarterback clean?

#6 The big storyline: The Raiders are looking to build on their comeback victory over the Jets, while the 49ers hope to return from their bye week ready to defend their home field. The availability of McCaffrey and Nick Bosa will be important factors to monitor.

Rich Perez filled in for Tony Renteria on the Las Vegas Raiders podcasts at http://www.sportsradioservice.com