Arizona Cardinals quarterback Kyler Murray (1) tosses the football in practice back on Wed Aug 12th with Cardinals head coach Kliff Kingsbury watching. Murray and the Cardinals are headed to Levis Stadium against the San Francisco 49ers for Sun Sep 13th’s opener (AP News file photo)

By Jeremiah Salmonson

The San Francisco 49ers will take on the Arizona Cardinals this Sunday in the smoke ravaged Bay Area.

The game itself has a number of intriguing story lines.

First, this will be the first game for the new for newly acquired De’Andre Hopkins for the Cardinals. He is of course paired with once drafted A’s prospect Kyler Murray.

Murray of course is now known for his multifaceted approach to the QB position for the Cardinals. His arm and legs paired with a newly acquired receiver will be an exciting watch for Cardinals fans.

On the flip side this will be the first game since the 49ers lost a heart breaking Super Bowl to the Kansas City Chiefs. The 49ers will look to continue their winning ways as anything but another trip to the super bowl would be a let down.

With the departure of Emmanuel Sanders in the off-season the 49ers will need to rely more heavily on second year receiver Deebo Samuel. The 49ers feel confident with him having received great production from him at the end of last year.

The game is set to take place Sun Sep 13 at 1:25 PM PST at Levis Stadium in Santa Clara.