San Francisco 49ers podcast David Zizmor: Ayiuk’s demise didn’t distract the team at all

San Francisco 49ers wide receiver Brandon Aiyuk (11) in the first half against the Arizona Cardinals at Levi Stadium in Santa Clara on Oct 5, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 How much is the Brandon Aiyuk situation going to impact the San Francisco 49ers as Aiyuk and the 49ers are headed for a split. Aiyuk had been work for a resolution as Aiyuk has one more year left on his contract and is out on the reserve/left team list and cannot return for the rest of the season.

#2 49ers head coach Kyle Shanahan said on Rickey Pearsall with a right knee cruciate ligament injury.Peasall caught an eight yard pass during the first play and caught six passes for 96 yards in the 49ers win over the Tennessee Titans 37-24 last Sunday.

#3 Next up for the 49ers (10-4) the Indianapolis Colts (8-6) at Lucas Oil Field for Monday Night Football on Dec 22. The Colts have lost five of their last six games and have lost four in a row the 49ers are catching the Colts in the middle of a slump.

Join David Zizmor for the 49ers podcasts each Wednesday at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: 49ers Purdy 3 TDs beat Titans 37-24

San Francisco 49ers quarterback Brock throws against the Tennessee Titans safety Amani Hooker (37) at Levi Stadium in Santa Clara on Sun Dec 14, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 San Francisco 49ers quarterback Brock Purdy connected on multiple touchdown passes today — what adjustments did the 49ers make offensively that helped him find success against the Tennessee Titans’ secondary?

#2 49ers running back Christian McCaffrey how he look physically during today’s game and what did it mean for him to find the end zone against Tennessee?

#3 It’s off the Indianapolis and the Colts on Monday Night Football Dec 22 at Lucas Oil Field. The Colts are 8-6 and are on a four game losing streak having lost to the Seattle Seahawks 18-16 in Seattle Sunday. How do you see this match up in Indianapolis next week?

David Zizmor does the SF 49ers podcasts after every home and away game at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Will 49ers make easy work of 1-11 Titans in Santa Clara Sunday?

San Francisco 49ers quarterback Brock Purdy (13) throws a pass against the Cleveland Browns on Sun Nov 30, 2025 at Huntington Bank Field in Cleveland. The 49ers could go into their bench if they overwhelm the Tennessee Titans this Sun Dec 14, 2025 at Levi Stadium (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 Can Brock Purdy bounce back and lead the 49ers’ offense after the bye week against the Titans’ defense?

#2 How will Christian McCaffrey and Kyle Juszczyk be used to exploit Tennessee’s run defense — will the 49ers lean on the ground game?

#2 With pass-rush numbers down for San Francisco this season, can Nick Bosa pressure the Titans’ quarterback enough to disrupt their offense?

David Zizmor does the 49ers podcasts each week at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: 49ers host 1-11 Titans who have a good offensive front Sun Dec 14 in Santa Clara

San Francisco 49ers quarterback Brock Purdy (13) is thrilled after the 49ers defeated the Cleveland Browns at Huntington Bank Field in Cleveland on Sun Nov 30, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 With Christian McCaffrey healthy and expected to feature prominently in the run game, how might his usage shape the 49ers’ offensive strategy against the Titans’ defense on Sun Dec 14?

#2 Can Brock Purdy — given his recent performances — build on momentum in the passing game to exploit Tennessee’s secondary, or will the 49ers lean more on their ground attack with McCaffrey?

#3 Considering the 49ers’ offensive line and running back depth beyond McCaffrey, Isaac Guerendo, Jordan James, how might they balance carries and keep the offense fresh against a physical Titans front?

Join David Zizmor for the San Francisco 49ers podcasts each Wednesday at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor Sun Nov 30, 2025: 49ers score in each quarter to beat Browns 26-8

San Francisco 49ers quarterback Brock Purdy (13) is sacked by the Cleveland Browns defensive end Myles Garrett (middle right) in the second half at Huntington Bank Field in Cleveland on Sun Nov 30, 2025 (AP News photo)

SF 49ers podcast David Zizmor:

#1 The San Francisco 49ers (9-4) picked up their ninth win of the 2025 season with a win over the Cleveland Browns (3-9) 26-8 at Huntington Bank Field and from the looks of it the 49ers made easy work of the Browns.

#2 The 49ers were able to score in each of the four quarters and quarterback Brock Purdy was 16-29 for 168 yards and threw for one touchdown.

#3 Up next for the 49ers they host the Tennessee Titans (1-11) in Santa Clara. The Titans are having a rough season winning one game out of 12 games for the season. The Titans lost a tough on Sunday to the Jacksonville Jaguars 25-3. The Titans are suffering from both sides of the football. How do you see this one next Sun Dec 14.

Join David Zizmor for the 49ers podcasts after every home and away game at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Could 49ers have their hands full in Cleveland on Sunday?

San Francisco 49ers wide receiver Jauan Jennings (15) pushes off on the Carolina Panthers cornerback Mike Jackson (right) in the second half at Levi Stadium on Mon Nov 24, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 David you said that their San Francisco 49ers (8-4) next opponent the Cleveland Browns (3-8) are a dangerous opponent what most will the 49ers need to fear in this upcoming game this Sunday?

#2 The Browns running back Quinshon Judkins against the Las Vegas Raiders last Sunday carried for 16 carries 47 yards and scored two touchdowns. No doubt the 49ers defense will be keying in on Judkins.

#3 The 49ers are coming off a win over the Carolina Panthers (6-6) on Monday Night Football 20-9 they head to Cleveland next Sunday and like you talked about last Sunday the Browns have improved and under center is no different with quarterback Shedeur Sanders 11-20, 209 yards, and one touchdown last Sunday against the Raiders.

David Zizmor does the San Francisco 49ers podcast at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Purdy good enough to get 49ers over Panthers 20-9 despite 3 interceptions

Carolina Panthers defensive end Derrick Brown blocks a pass thrown by San Francisco 49ers quarterback Brock Purdy (13) in the first half at Levi Stadium in Santa Clara on Monday Night Football Nov 24, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 The San Francisco 49ers (8-4) held the Carolina Panthers (6-6) to just six points how much do you attribute to the 49ers defense in picking up this 20-9 win?

#2 On offense the 49ers got a a touchdown in each of the first and third quarters. Quarterback Brock Purdy didn’t break the scales of most touchdowns in a game but was 23-32 for 193 yards, and was picked off three times.

#3 Next up for the 49ers the Cleveland Browns (3-8). The Browns are coming off a 24-10 against the Las Vegas Raiders (2-9) on Sunday. The Browns with the win over the Raiders snapped a three game losing streak. How do you see this match up between the 49ers and Browns this Sunday at Huntington Bank Field?

Join David Zizmor for the 49ers podcast following each home and away game at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Pineiro will sit out Monday Night Football due to hamstring injury; Shanahan auditioning kickers this week

San Francisco 49ers kicker (on top) is carried off the field after hitting a game winning kick against the Arizona Cardinals at Levi Stadium in Santa Clara on Sun Sep 21, 2025. Pineiro will be out with a hamstring injury and is week to week and will miss Monday Night Football Nov 24, 2025 against the Carolina Panthers at Santa Clara. (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 With kicker Eddy Pineiro out of the line up this Monday night against the Carolina Panthers with a hamstring injury. Head coach Kyle Shanahan said that he’s bringing in some guys to work out and the 49ers are pushing to find a kicker before their next game on Monday Night Football.

#2 This week in an interview quarterback Brock Purdy said that he’s back into a rhythm and is moving forward. How much confidence after having such success against the Arizona Cardinals does Purdy have getting ready for Monday’s game?

#3 David, what your prediction now as it stands for Monday Night against the Carolina Panthers with Purdy back and the offense back on all cylinders?

Join David Zizmor for the 49ers podcasts Mondays at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Purdy doesn’t look like he’s missed a step

San Francisco 49ers quarterback Brock Purdy (left) gets congratulations from running back Christian McCaffrey (23) in the first half at State Farm Stadium in Glendale AZ on Sun Nov 16. 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 Well the one question that was answered Sunday was how would San Francisco 49ers quarterback (7-4) Brock Purdy do once he returned from his turf toe injury and the results were astonishing with a 41-22 win over the Arizona Cardinals (3-7).

#2 Purdy had himself an afternoon going 19-26, 200 yards, and three touchdowns. He looked like he hasn’t missed a step.

#3 Up next for the 49ers the Carolina Panthers 6-5-0 second in the NFC South at Levi Stadium next Mon Nov 24. How do you see this match up?

David Zizmor does the SF 49ers podcasts each Wednesday and after every home and away game at http://www.sportsradioservice.com

San Francisco 49ers podcast David Zizmor: Will injuries have an impact on 49ers as they meet Cardinals Sunday

San Francisco 49ers running back Christian McCaffrey (23) gives thanks to the Almighty after scoring a touchdown against the New York Giants in the fourth quarter Sun Nov 2, 2025 in East Rutherford NJ (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 With Christian McCaffrey still being one of the most versatile offensive weapons in the league, how will the 49ers deploy him against Arizona’s front-seven—and can he exploit any running-lane weaknesses in the Cardinals’ defense?

#2 Given that Mac Jones has been the primary quarterback this season (while Brock Purdy remains uncertain/injured) for San Francisco with 2,151 passing yards so far this year, how might the change in signal-caller impact the 49ers’ offensive rhythm and decision-making?

#3 On the defensive side, how well can the 49ers limit the Cardinals’ offense—especially in the passing game, given Arizona is allowing about 223.7 yards per game through the air so far?

David Zizmor does the San Francisco 49ers podcasts Wednesdays at http://www.sportsradioservice.com