San Francisco 49ers tight end Christian McCaffrey (23) bolts past the Indianapolis Colts defensive end Laiatu Latu (97) and and defensive tackle Grover Steward (90) in the first half at Lucas Oil Field in Indianapolis (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 The San Francisco 49ers (11-4) left little doubt and left it all on the Lucas Oil Field in Indianapolis with a crushing 48-27 win over the Indianapolis Colts (8-7) on Monday Night Football.

#2 San Francisco quarterback Brock Purdy had the hot hand and lots of protection throwing for five touchdown passes in getting the win against the Colts.

#3 Next up for the 49ers the Chicago Bears (11-4) at Levi Stadium on Sunday Night Football Dec 28th at 5:25pm PT. The Bears have won seven of their last eight games could this be a game that could go right down to the wire?

David Zizmor does the San Francisco 49ers podcast at http://www.sportsradioservice.com