San Francisco 49ers quarterback Brock throws against the Tennessee Titans safety Amani Hooker (37) at Levi Stadium in Santa Clara on Sun Dec 14, 2025 (AP News photo)

San Francisco 49ers podcast David Zizmor:

#1 San Francisco 49ers quarterback Brock Purdy connected on multiple touchdown passes today — what adjustments did the 49ers make offensively that helped him find success against the Tennessee Titans’ secondary?

#2 49ers running back Christian McCaffrey how he look physically during today’s game and what did it mean for him to find the end zone against Tennessee?

#3 It’s off the Indianapolis and the Colts on Monday Night Football Dec 22 at Lucas Oil Field. The Colts are 8-6 and are on a four game losing streak having lost to the Seattle Seahawks 18-16 in Seattle Sunday. How do you see this match up in Indianapolis next week?

David Zizmor does the SF 49ers podcasts after every home and away game at http://www.sportsradioservice.com