Los Angeles Rams quarterback Matt Stafford points in the direction where he wants his offense to go against the San Francisco 49ers defense at Levis Stadium in Santa Clara on Sun Nov 9, 2025 (AP News photo)

San Francisco 49ers podcast with David Zizmor:

#1 The San Francisco 49ers (6-4) got pulverized by the Los Angeles Rams (7-2) by nothing close 42-26. The Rams quarterback Matt Stafford had all day to throw and got great protection. Stafford was 24-26 for 280 yards and four touchdowns.

#2 Meanwhile 49ers quarterback Mac Jones had troubles trying to keep up with the Rams on the scoreboard and wasn’t able to connect to receivers as much as he would throwing 33-39 for 319 yards and three touchdowns.

#3 Up next for the 49ers it’s off to Arizona and State Farm Stadium in Glendale to face Arizona Cardinals quarterback Jacoby Brissett. The Cardinals lost a tough one on Sunday to the Seattle Seahawks getting 22 point beat down losing 44-22. How do you see this one next Sunday in Arizona?

Join David Zizmor for the San Francisco 49ers podcast after every home and away game at http://www.sportsradioservice.com