San Francisco 49ers back up quarterback Mac Jones (13) is out with a strained knee and the 49ers have numerous injuries up and down the roster going into week 3 of the pre season (AP News photo)

#1 The 49ers have injuries with four running backs, five of their defensive players are hurt, back up quarterback Mac Jones has a strained knee, and injuries at wide receiver.

#2 The 49ers tried to trade for Philadelphia Eagles wide receiver John Metchie but the Eagles dealt Metchie to the Houston Texans.

#3 How concerning is it to have so many injuries and it’s not even close to opening day yet is there doubt that the 49ers will be ready?

Join David Zizmor for the 49ers podcasts after every home and away game at http://www.sportsradioservice.com