The San Francisco 49ers wide receiver Deebo Samuel (19) was not at practice on Wednesday and Sanders will not play on Sunday for the opener against the Arizona Cardinals. Samuel is suffering from a foot injury. (file photo from fansided.com)

On the 49ers podcast with David:

#1 The 49ers are trying to be optimistic about the return of wide receivers Brandon Aiyuk (hamstring)  and Deebo Samuel (foot) both sat out of practice on Wednesday but could you see them getting in for the game on Sunday?

#2 Two more injuries to ask about is center Ben Garland who is listed to limited action and corner back Jason Verrett (hamstring).

#3 David talk about the defending against the pass and how you see the 49ers attempting to shutdown Arizona quarterback Klyer Murray and the pass?

Join David each Friday for the 49ers podcasts at http://www.sportsradioservice.com