Photo credit: ninerswire.usatoday.com

By Jeremy Harness

The last time the 49ers saw the Arizona Cardinals, they were embarrassed on their home field by a then-winless team, thus solidifying a lost season that hopes for a brighter future.

Since then, the Cardinals were blown out at home by a 2-4 Denver Broncos team, making the loss even worse.

The 49ers have a chance to gain a bit of redemption Sunday afternoon as they go on the road to face Arizona, a team that is now in complete disarray. To highlight matters, rookie Josh Rosen has struggled as the team’s new starting quarterback, and All Pro corner Patrick Peterson has expressed a strong desire to be traded away.

There are no such issues or drama in Santa Clara, but the injury situation remains the same.

Running back Matt Breida went down with another ankle injury in last Sunday’s blowout loss to the Rams, and he did not practice Wednesday because if it. At press time, he is questionable to play at Arizona this Sunday.

However, coach Kyle Shanahan said Wednesday that Breida’s condition has improved in the days following Sunday’s game, holding out hope that he could see action this weekend.

Meanwhile, receiver Pierre Garcon, who has contributed next to nothing this season, is doubtful to play against the Cardinals as he is dealing with a knee injury.

On the defensive side, there was good news and bad news. Cornerback Jimmie Ward made his way back to the practice field on Wednesday while working his way back from a hamstring ailment, but safety Adrian Colbert was placed on the injured-reserve list this week with a high ankle sprain.

He will be eligible to return for Week 16, per injured-reserve rules, but there is no telling if he will play once he is eligible.

For the Cardinals, the biggest names on the injury report are receiver Larry Fitzgerald, who did not practice Wednesday with a hamstring injury, while safety Tre Boston was held out of practice while he deals with shoulder and rib ailments.