Buffalo Bills running back LeSean McCoy (25) runs with the ball as Oakland Raiders middle linebacker NaVorro Bowman (53), safety Shalom Luani (26) and cornerback T.J. Carrie (38) try to bring him down during the first half of an NFL football game, Sunday, Oct. 29, 2017, in Orchard Park, N.J. (AP Photo/Adrian Kraus)

By Jeremy Kahn

OAKLAND — After a huge come-from-behind victory over the Kansas City Chiefs, the Oakland Raiders headed out on the road for a two-game road trip and their first stop was not a good one.

Rookie linebacker Matt Milano returned a fumble 40 yards to the end zone, helping the Buffalo Bills defeat the Raiders 34-14 at New Era Field.

The Milano fumble was one of four Raiders turnovers on the afternoon, as the Raiders have now lost four out of their last five games since beginning the season with a 2-0 record.

Tyrod Taylor also threw a six-yard touchdown pass to former Raiders wide receiver Andre Holmes. Taylor also scored on a one-yard run, as they improved their record to 5-2 on the season.

LeSean McCoy picked up a season-high 151 yards and also scored on a 48-yard touchdown run to help the Bills to the 20-point victory.

The Bills are now 4-0 at home, their best start at home since they started 5-0 during the 1995 season.

This is the best Bills start during their 17-year playoff drought, the longest drought by any team in the four major sports.

Derek Carr went 31-for-48 for 313 yards passing and a four-yard pass to DeAndre Washington. Carr also threw two interceptions on the afternoon. Following a Jamize Olawale touchdown run, the Raiders failed to get on the board on their next eight possessions.

Those next eight drives ended with four punts, three turnovers and they were unable to score at the end of the first half.

Without the suspended Marshawn Lynch, the Raiders gained just 54 yards on the ground.

NOTES: With their next game in Miami against the Dolphins, the Raiders will stay on the east coast for the next week and will be in Sarasota, FL. until they head to Miami before their Sunday Night matchup.

Rookie Shalom Luani started in place of Karl Joseph, who missed the game due to a groin injury and Dexter McDonald started for David Amerson, was out of the game with a foot injury.