By Jeremy Kahn

AP photo: Former Boston Red Sox Jake Peavy pitching for the San Francisco Giants delivers a pitch in the first inning in Fenway Park on Tuesday night

BOSTON-Jake Peavy would love to have two pitches back that he threw on the night in his return to Fenway Park.

After retiring the first eight batters, Peavy gave up a solo home run to Brock Holt on a 3-2 pitch in the bottom of the third inning for the only run that the Boston Red Sox would need, as they defeated the San Francisco Giants 4-0 before a sellout crowd of 38,082, the largest crowd of the season at Fenway Park.

“Funny how that one played out, set up an inning with the guy I want to face in that situation, did get the pitch where it needed to be, Brock had a good at-bat earlier,” said Peavy.

This was the fourth consecutive loss for the Giants, the team’s longest losing streak since losing five in a row from April 17-21. Also it was the fifth shutout of the season against the Giants, and the first since June 20, when they were shutout versus the Pittsburgh Pirates at PNC Park.

As for the Red Sox, they have won seven out of their last eight games and nine out of their last 11 and are now a season-high 13 games over .500.

In two of the four games that the Giants have played at Fenway Park, they have been shutout by the Red Sox, including a 1-0 loss by tomorrow’s starting pitcher Matt Cain, who allowed a solo home run to Manny Ramirez in the bottom of the fourth inning, for the only run of the game.

Of all the players who played in that game for both the Giants and Red Sox, the only ones left are Cain for the Giants, Ortiz and Pedroia for the Red Sox. While Barry Bonds was the designated hitter and he went 0-for-3 with a walk and a strikeout.

The Giants are now 6-7 in interleague play, and 1-2 versus the Red Sox this season. Overall, the Giants fall to 5-10 against the Red Sox.

Peavy got into trouble in the bottom of the fourth inning, as he walked Dustin Pedroia, then Xander Bogaerts singled and then David Ortiz launched a 451-foot home run into the right center field seats for his 23rd home run of the season.

It was a bittersweet homecoming for Peavy, who helped lead the Red Sox to their third World Championship in 10 years in 2013 and was given a rousing ovation by the Red Sox fans.

“That was awesome, I love Fenway Park to comeback here as a visitor, tonight was different; because you are in compete mode,” said Peavy.

The Red Sox played a video that showed Peavy when he played for the Red Sox, and they put a sign on the scoreboard that said “Welcome back Jake Peavy, 2013 World Champion.”

In all, Peavy went six innings, allowing those four runs on just three hits, walking just one and striking out six.

Angel Pagan went 2-for-4, for his second multi-hit game over his last three games. Denard Span also went 2-for-4, as he raised his average to .316 all-time, as he is 18-for-57 in 15 career games all-time at Fenway Park.

Rick Porcello pitched a great game for the Red Sox, as he went 6.1 innings, scattering four hits, walking just two and striking out three. Porcello raised his record to 9-0 in 10 starts at Fenway Park this season, becoming the first Red Sox pitcher since Dennis Eckersley in 1978 to begin a season 9-0.

It was the 526th career home run for Ortiz, his fourth in his last five games. Ortiz tied Tony Gwynn for 98th place in MLB history with 1,383 runs scored.

Peavy was not the only Giants player honored with a video tribute and a rousing ovation, as Javier Lopez, who pitched for the Red Sox during their 2007 World Championship was shown appreciation as he came on to face the Red Sox in the bottom of the seventh inning.